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Exosomes or PRP for Thinning Hair: What the Research Says

Two scalp treatments, one much newer than the other. Here is where the evidence stands and how we choose between them.
Exosomes or PRP for Thinning Hair What the Research Says

Read about hair treatments for ten minutes and you will meet both of these. PRP has been around long enough that most people have heard of it.

Exosomes are newer, more expensive, and discussed with far more certainty than the evidence supports.

Here is the plain version.

What PRP is

PRP stands for platelet rich plasma. We take a small amount of your blood and spin it, so the platelets separate out and concentrate. That concentrate goes into the scalp where hair is thinning.

Platelets bring growth factors with them. The idea is to put a lot of them where you want follicles to be more active.

It comes from you, which is the part patients usually care about most. Nothing is being introduced that was not already yours.

What exosomes are

Exosomes are much smaller. They are tiny packages that cells release to signal other cells, and they contain proteins and genetic messengers.

The exosome products used in scalp treatments do not come from your own blood. They are prepared from cell sources and supplied as a product.

They go into the scalp, not into the bloodstream, and how they get there varies by clinic. Microneedling is the usual route. A needle-free jet device is the other, and we offer both.

So the mechanism is a step removed from PRP. PRP delivers a concentrate of your own platelets. Exosomes deliver signalling packages that tell cells what to do.

What the research supports

This is where most articles get vague. Here is the shape of it.

PRP has the longer track record. It has been studied for scalp hair for years and used in clinics for years, and a reasonable body of published work stands behind it.

The findings are not unanimous and results vary between people. It has been examined properly and repeatedly.

Exosomes have much less behind them. The laboratory rationale is interesting and the early clinical work is encouraging.

But it is early, the studies are smaller, and there is no standard product. That makes results hard to compare between clinics. Two exosome treatments at two clinics may be different treatments.

That is no reason to dismiss them. It is a reason to say plainly that you are paying more for less evidence, so you know that when you decide.

We would sooner tell you before you book than after.

How we choose

In practice, the choice is less about which is better and more about what your scalp is doing.

  • Is there hair left to work with. Both of these support follicles that are alive and

underperforming. Neither brings back a follicle that is gone. It is why we look before we recommend.

  • What else is going on. If something underneath is driving the thinning, treating the scalp

without addressing that is the expensive way round.

  • Whether you want something from your own body. Some people care about this a lot. It is a

legitimate reason to choose PRP and we do not argue with it.

  • How you feel about newer treatments. Some people want the most established option. Others are

comfortable with newer. Both positions are reasonable.

  • How you feel about needles. PRP is an injection and there is no way around that. Exosomes can go

in without a needle, using JetPeel, and for some people that settles it on its own.

  • What you are prepared to commit to. Neither of these is a single visit.

Doing both

They are not mutually exclusive. Pairing exosomes with microneedling is a common approach, because the microneedling creates channels for the product and the product does the signalling.

Whether combining suits you is a scalp by scalp question, not a rule. It gets decided in the room, not in an article.

The part nobody likes

Neither of these is fast, and neither is permanent.

Hair grows slowly. Any treatment aimed at follicles is judged over months, not weeks.

The first sign of it working is usually that shedding slows. New hair comes later.

Both are courses, and both need maintenance to protect what you gain. A clinic that tells you otherwise is selling, and it is not explaining.

Where to start

The useful first step is not choosing between them. It is finding out whether either one suits what is happening on your scalp, because for some patterns neither does.

Our PRP hair restoration in London, Ontario page explains how that treatment works. Our exosome therapy page covers how we use exosomes for hair, and the two ways we deliver them.

If you are not sure which question you are asking yet, start with the assessment. That is what it is for.

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